Polyamines in Psoriasis
نویسندگان
چکیده
منابع مشابه
Polyamines in inflammation
esults on page 257 by Soulet and Rivest implicate polyamines in controlling immune responses in the brain. Their results suggest that polyamine synthesis, if left unchecked, can cause damaging inflammatory responses reminiscent of neurodegenerative disorders. Recognition of bacterial and viral pathogens by microglial cells, the brain’s equivalent of macrophages, elicits a cascade of gene expres...
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The total cellular mass of the small intestine is well controlled and can adapt, with hypo- or hyperplasia, to a wide variety of stimuli. Luminal nutrients, hormonal factors and pancreatic and biliary secretions have all been implicated in the regulation of intestinal mucosal growth. The polyamines (putrescine, spermidine and spermine) and the key enzyme controlling their synthesis (ornithine d...
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The recent report, “Serum prolactin level in psoriasis”, is very interesting 1. Ghiasi et al. concluded that “it seems that while intracutaneous prolactin may contribute to the pathogenesis of psoriasis, the probable role of pituitary-produced circulating prolactin in the disease process needs further investigation .” There are some concerns on this report. First, although Ghiasi et al. have st...
متن کاملPolyamines in living organisms
Natural polyamines, putrescine, spermidine and spermine are ubiquitous cell components essential for normal cellular functions and growth. Chemically these compounds are very simple organic aliphatic cations and fully protonated under physiological conditions. There is a strong correlation between proliferation rate of the cells and their polyamine contents. Adjustments of intracellular concent...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1983
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12521665